Does Abiraterone Have to Be in the Refrigerator? A Complete Guide
When prescribed a new medication like abiraterone, patients often have questions about proper storage, dosage, and usage to ensure its effectiveness. One frequently asked question is, “Does abiraterone have to be in the refrigerator?” In this article, we’ll answer this question in detail and explore best practices for storing abiraterone, ensuring the medication remains safe and effective.
We’ll also delve into related topics, including:
- What abiraterone is and how it works.
- Why proper storage matters.
- Common misconceptions about medication storage.
- The role of temperature and humidity in preserving medications.
- Frequently asked questions about abiraterone.
Let’s start by understanding what abiraterone is and why proper storage is essential.

What is Abiraterone and How Does It Work?
Abiraterone acetate, often sold under the brand name Zytiga, is a prescription medication primarily used in the treatment of prostate cancer. It works by inhibiting the production of androgens (male hormones) in the body, which can fuel the growth of prostate cancer cells. Abiraterone is typically prescribed alongside other medications like prednisone to enhance its efficacy and minimize side effects.
Since abiraterone is a life-saving medication for many individuals, proper storage is critical to maintaining its potency. Incorrect storage can reduce its effectiveness and lead to suboptimal results in treatment.
Does Abiraterone Have to Be in the Refrigerator?
The straightforward answer is: No, abiraterone does not need to be refrigerated. According to the manufacturer’s guidelines and product labeling, abiraterone should be stored at room temperature, typically between 68°F to 77°F (20°C to 25°C). However, short-term variations in temperature (ranging from 59°F to 86°F or 15°C to 30°C) are generally acceptable.
Why Abiraterone Doesn’t Require Refrigeration
Abiraterone acetate tablets are formulated to remain stable at room temperature. Refrigerating the medication is not only unnecessary but could potentially expose the tablets to moisture, which might degrade their quality. This is especially true in modern refrigerators where condensation can occur. Instead, the drug is best kept in a cool, dry place away from direct sunlight.
Best Practices for Storing Abiraterone
Proper storage of abiraterone ensures its chemical integrity and efficacy. Follow these guidelines to ensure the medication remains effective throughout its shelf life:
1. Store at Room Temperature
As mentioned, keep abiraterone tablets at a stable room temperature, ideally between 68°F to 77°F. Avoid extreme temperatures, as fluctuations could compromise the medication’s stability.
2. Avoid Moisture
Moisture is a common culprit in medication degradation. Do not store abiraterone in bathrooms, kitchens, or any other areas prone to high humidity.
3. Keep in Original Packaging
Always store abiraterone in its original container, which is designed to protect the tablets from environmental factors such as light and air. The bottle often includes a desiccant to absorb moisture, which further ensures the medication stays dry.
4. Avoid Direct Sunlight
Exposure to direct sunlight can cause heat buildup and may degrade the active ingredients in abiraterone. Always store the medication in a shaded, cool place.

5. Keep Out of Reach of Children
As with any prescription medication, abiraterone should be kept out of reach of children and pets to prevent accidental ingestion.
Why Proper Storage of Medications is Critical
Improper storage of medications can have significant consequences. Here’s why it’s important to follow storage instructions carefully:
1. Loss of Potency
If abiraterone is exposed to high temperatures, humidity, or sunlight, its active ingredients may degrade, reducing its effectiveness in treating prostate cancer. A weakened medication can lead to suboptimal treatment outcomes.
2. Risk of Side Effects
Degraded medications may produce unintended byproducts that can increase the likelihood of side effects or adverse reactions.
3. Financial Impact
Abiraterone is an expensive medication, and improper storage leading to spoilage means wasted money. Ensuring proper storage safeguards your investment in your health.

Common Misconceptions About Storing Medications
When it comes to storing prescription drugs, there are many myths and misconceptions. Let’s debunk a few related to abiraterone and other medications:
Myth #1: All Medications Need Refrigeration
Many people believe that medications should be stored in the refrigerator to prolong their shelf life. While this is true for certain drugs like insulin or some liquid antibiotics, it is not applicable to abiraterone. Room temperature is ideal for this particular medication.
Myth #2: Medicine Cabinets are Ideal Storage Locations
The term “medicine cabinet” is a bit misleading. Bathrooms tend to have fluctuating temperatures and high humidity levels, which can degrade most medications. A dry, cool place such as a drawer or cupboard outside the bathroom is a better choice.
Myth #3: Freezing Medications Improves Their Shelf Life
Freezing medications can cause crystallization or other chemical changes that may reduce their effectiveness or make them unsafe to use. Abiraterone should never be frozen.
Other Important Considerations When Using Abiraterone
Proper storage is just one aspect of ensuring abiraterone remains effective. Here are a few additional tips to maximize the benefits of this medication:
1. Take Abiraterone as Directed
Abiraterone is typically taken once daily on an empty stomach, at least one hour before or two hours after a meal. Follow your doctor’s instructions closely to achieve the best results.
2. Use Abiraterone Alongside Prednisone
Prednisone is often prescribed alongside abiraterone to help manage potential side effects. Be sure to take both medications exactly as prescribed.
3. Schedule Regular Check-Ups
Your doctor will monitor your progress and adjust your treatment plan as necessary. Regular blood tests may also be required to assess liver function and other factors.

Conclusion
To summarize, abiraterone does not need to be refrigerated. It is best stored at room temperature, in its original packaging, and away from moisture, light, and heat. Proper storage ensures the medication remains effective and safe to use throughout its prescribed duration.
If you’re ever unsure about how to store abiraterone or any other medication, consult your doctor or pharmacist for guidance. Proper storage practices are an essential part of managing your treatment and maximizing the benefits of this important medication.
By following these guidelines, you can ensure your abiraterone remains potent, allowing you to focus on your treatment and overall health.
1. What Should I Do if I Accidentally Store Abiraterone in the Refrigerator?
If you accidentally store abiraterone in the refrigerator for a short period, it is unlikely to cause any harm. However, prolonged refrigeration could expose the tablets to moisture, which might reduce their effectiveness. Always consult your pharmacist or doctor if you’re unsure whether the medication is still safe to use.
2. Can I Travel With Abiraterone?
Yes, you can travel with abiraterone. Ensure the medication remains within the recommended temperature range during transit. Use a travel-friendly pill container or keep the original packaging with you.
3. What Happens If Abiraterone Is Exposed to High Temperatures?
Prolonged exposure to high temperatures (above 86°F or 30°C) can degrade abiraterone. If this occurs, consult your pharmacist for advice on whether the medication is still safe to use.
4. How Long Can I Store Abiraterone After Opening the Bottle?
Once opened, abiraterone tablets should be stored in the same manner as before: in their original packaging, at room temperature, and away from moisture and light. Check the expiration date on the bottle and do not use the medication beyond that date.